Radiolabel validation of cortisol in the hair of rhesus monkeys

• Published in: Psychoneuroendocrinology Vol. 97; pp. 190 - 195
• Main Authors: Kapoor, Amita, Schultz-Darken, Nancy, Ziegler, Toni E.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.11.2018
• Subjects: Animals; Behavior, Animal; Cortisol; Cortisone - analysis; Glucocorticoids; Hair - chemistry; Hair cortisol; Hair hormones; HPLC-UV; Hydrocortisone - analysis; Hydrocortisone - blood; Hypothalamo-Hypophyseal System; Macaca mulatta - metabolism; Male; Pituitary-Adrenal System; Radiolabel; Saliva - chemistry; Tritium; Validation; Validation; Radiolabel; Cortisol; HPLC-UV; Hair cortisol; Hair hormones

•Systemically administered [3H]-cortisol was detected in the hair as cortisol.•Demonstrated for that hair cortisol is representative of circulating cortisol.•[3H]-cortisol was incorporated into hair as cortisone.•[3H]-cortisol was also incorporated into hair as other unknown cortisol metabolites. An...