Neuromedin U, a Key Molecule in Metabolic Disorders

• Published in: International journal of molecular sciences Vol. 22; no. 8; p. 4238
• Main Authors: Teranishi, Hitoshi, Hanada, Reiko
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.04.2021; MDPI
• Subjects: Animal behavior; Body weight; brain reward system; Calories; Circadian rhythms; Energy; Energy expenditure; Energy metabolism; Feeding behavior; Homeostasis; Hypothalamus; Inflammation; Insulin; Insulin secretion; Ligands; Metabolic disorders; Muscle contraction; Nervous system; Neuromedin; neuropeptide; Neuropeptides; NMU system; Obesity; Peptides; Physiology; Public health; Review; Smooth muscle; Spinal cord; Spleen; Stress response; Thermogenesis; Thyroid gland; brain reward system; NMU system; inflammation; neuropeptide; feeding behavior; insulin secretion; energy expenditure; obesity

Obesity is now a public health concern. The leading cause of obesity is an energy imbalance between ingested and expended calories. The mechanisms of feeding behavior and energy metabolism are regulated by a complex of various kinds of molecules, including anorexigenic and orexigenic neuropeptides....