Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle

• Published in: Journal of applied physiology (1985) Vol. 115; no. 10; pp. 1562 - 1571
• Main Authors: Picard, Martin, Gentil, Benoit J., McManus, Meagan J., White, Kathryn, St. Louis, Kyle, Gartside, Sarah E., Wallace, Douglas C., Turnbull, Douglass M.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 15.11.2013
• Subjects: Animal subjects; Animals; Blood Glucose - metabolism; Cell culture; Energy Metabolism; Exercise; Female; GTP Phosphohydrolases - metabolism; Lipid Metabolism; Membrane Fusion; Membranes; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Mitochondria; Mitochondria, Muscle - metabolism; Mitochondria, Muscle - ultrastructure; Mitochondrial Dynamics; Mitochondrial Membranes - metabolism; Mitochondrial Membranes - ultrastructure; Mitochondrial Size; Morphology; Muscle Contraction; Muscle, Skeletal - metabolism; Muscle, Skeletal - ultrastructure; Musculoskeletal system; Physical Conditioning, Animal; Proteins; Time Factors; fusion; exercise; skeletal muscle; metabolic state; mitochondrial dynamics

A unique property of mitochondria in mammalian cells is their ability to physically interact and undergo dynamic events of fusion/fission that remodel their morphology and possibly their function. In cultured cells, metabolic perturbations similar to those incurred during exercise influence mitochon...