Socio-demographic and clinical predictors of non-response/non-remission in treatment resistant depressed patients: A systematic review

• Published in: Psychiatry research Vol. 240; pp. 421 - 430
• Main Authors: De Carlo, Vera, Calati, Raffaella, Serretti, Alessandro
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 30.06.2016
• Subjects: Antidepressant; Antidepressive Agents - therapeutic use; Anxiety - complications; Depression; Depressive Disorder, Major - complications; Depressive Disorder, Major - drug therapy; Depressive Disorder, Treatment-Resistant - complications; Depressive Disorder, Treatment-Resistant - drug therapy; Hospitalization; Humans; Personality; Predictors; Psychiatry; Treatment resistant depression; Antidepressant; Depression; Treatment resistant depression; Predictors

Up to one third of patients adequately treated for Major Depressive Disorder (MDD) do not respond to multiple interventions. Many studies investigated predictors in MDD outcome, but no study focused on predictors of non-response or non-remission to antidepressants in subjects with treatment resistan...