Omicron SARS-CoV-2 variant: Unique features and their impact on pre-existing antibodies

• Published in: JOURNAL OF AUTOIMMUNITY Vol. 126; p. 102779
• Main Authors: Kannan, Saathvik R., Spratt, Austin N., Sharma, Kalicharan, Chand, Hitendra S., Byrareddy, Siddappa N., Singh, Kamal
• Format: Journal Article Publication
• Language: English
• Published: England Elsevier Ltd 01.01.2022
• Subjects: Antibodies, Viral - immunology; B.1.1.529; Binding Sites; COVID-19; COVID-19 - immunology; COVID-19 - virology; Humans; Mutation; Omicron variant; Phylogeny; Protein Structure, Tertiary; SARS-CoV-2; SARS-CoV-2 - genetics; Spike Glycoprotein, Coronavirus - genetics; Variants; COVID-19; Omicron variant; Variants; SARS-CoV-2; B.1.1.529

Severe Acute Respiratory Coronavirus (SARS-CoV-2) has been emerging in the form of different variants since its first emergence in early December 2019. A new Variant of Concern (VOC) named the Omicron variant (B.1.1.529) was reported recently. This variant has a large number of mutations in the S pr...