Human Obesity and Type 2 Diabetes Are Associated With Alterations in SREBP1 Isoform Expression That Are Reproduced Ex Vivo by Tumor Necrosis Factor-α - Sewter, Ciaran; Berger, Dirk; Considine, Robert V.; Medina, Gema; Rochford, Justin; Ciaraldi, Theodore; Henry, Robert; Dohm, Lynis; Flier, Jeffrey S.; O’Rahilly, Stephen; Vidal-Puig, Antonio J. (Diabetes (New York, N.Y.), 2002)
Keywords: Adipocytes - metabolism; Adipose tissues; Adult; Biological and medical sciences; CCAAT-Enhancer-Binding Proteins - genetics; Cholesterol; Diabetes Mellitus - genetics; Diabetes Mellitus, Type 2 - genetics; DNA-Binding Proteins - genetics; Fatty acid metabolism; Female; Gene Expression Regulation - drug effects; Humans; Insulin; Male; Obesity; Obesity - genetics; Obesity, Morbid - genetics; Physiological aspects; Protein Isoforms - genetics; Reference Values; RNA, Messenger - genetics; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha - pharmacology; Type 2 diabetes; United States