Primary leiomyoma of the liver in an immunocompetent patient
Primary leiomyoma of the liver (PLL) is a rare benign tumor occurring in immunosuppressed people. From 1926 less than fifty cases are reported in the scientific literature and about half are in immunocompetent patients. Etiology of this kind of lesion is not yet well known. We report a case of prima...
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Published in | Intractable & Rare Diseases Research Vol. 9; no. 4; pp. 251 - 255 |
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Main Authors | , , , , , , , , |
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International Research and Cooperation Association for Bio & Socio-Sciences Advancement
31.10.2020
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Abstract | Primary leiomyoma of the liver (PLL) is a rare benign tumor occurring in immunosuppressed people. From 1926 less than fifty cases are reported in the scientific literature and about half are in immunocompetent patients. Etiology of this kind of lesion is not yet well known. We report a case of primary hepatic leiomyoma in a 60-year-old immunocompetent woman. The patient presented with lipothymia with unexpected vomiting. She underwent an ultrasound (US), and a computed tomography (CT) scan that revealed the presence of a single, solid lesion about 9 cm located between the S5 and S8 segment of the liver. It showed a well-defined, heterogeneous hypodensity with internal and peripheral enhancement and various central hypoattenuating areas and no wash-out in the portal and the late phases. Because of her symptoms and the risk of malignancy, the patient underwent a surgical liver resection. Histological diagnosis was primary leiomyoma of the liver. The patient had an uneventful recovery and was discharged after 7 days. At 30 months follow-up there were no symptoms and no evidence of disease. Leiomyoma of the liver is a rare benign neoplasm of which clinical symptoms are nonspecific and the exact radiological diagnosis still remains a challenge for radiologists. Etiology is still unclear and usually PLL represents an incidental diagnosis. Surgery plays a primary role not only in the treatment algorithm, but also in the diagnostic workout. |
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AbstractList | Primary leiomyoma of the liver (PLL) is a rare benign tumor occurring in immunosuppressed people. From 1926 less than fifty cases are reported in the scientific literature and about half are in immunocompetent patients. Etiology of this kind of lesion is not yet well known. We report a case of primary hepatic leiomyoma in a 60-year-old immunocompetent woman. The patient presented with lipothymia with unexpected vomiting. She underwent an ultrasound (US), and a computed tomography (CT) scan that revealed the presence of a single, solid lesion about 9 cm located between the S5 and S8 segment of the liver. It showed a well-defined, heterogeneous hypodensity with internal and peripheral enhancement and various central hypoattenuating areas and no wash-out in the portal and the late phases. Because of her symptoms and the risk of malignancy, the patient underwent a surgical liver resection. Histological diagnosis was primary leiomyoma of the liver. The patient had an uneventful recovery and was discharged after 7 days. At 30 months follow-up there were no symptoms and no evidence of disease. Leiomyoma of the liver is a rare benign neoplasm of which clinical symptoms are nonspecific and the exact radiological diagnosis still remains a challenge for radiologists. Etiology is still unclear and usually PLL represents an incidental diagnosis. Surgery plays a primary role not only in the treatment algorithm, but also in the diagnostic workout. |
Author | Pattaro, Giada Nicosia, Simone D'Annibale, Marco Grazi, Gian Luca Manzi, Emy Marino, Mirella Coletta, Diego Parrino, Chiara Oddi, Andrea |
Author_xml | – sequence: 1 fullname: Coletta, Diego organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 2 fullname: Parrino, Chiara organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 3 fullname: Nicosia, Simone organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 4 fullname: Manzi, Emy organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 5 fullname: Pattaro, Giada organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 6 fullname: Oddi, Andrea organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 7 fullname: D'Annibale, Marco organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 8 fullname: Marino, Mirella organization: Department of Pathological Anatomy, IRCCS - Regina Elena National Cancer Institute, Rome, Italy – sequence: 9 fullname: Grazi, Gian Luca organization: Hepatopancreatobiliary Surgery, IRCCS - Regina Elena National Cancer Institute, Rome, Italy |
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Cites_doi | 10.1007/BF02011979 10.1056/NEJM199501053320103 10.1056/NEJM199501053320104 10.1136/bcr.09.2008.0898 10.1016/S0046-8177(74)80105-X 10.1155/1989/45978 10.1097/00007890-199602150-00036 10.1542/peds.90.3.460 10.1007/s10140-002-0214-y 10.1155/2014/959202 10.1097/00002030-199112000-00011 10.3748/wjg.v19.i25.4094 10.1097/00000478-199611000-00015 10.1016/S0399-8320(04)95200-1 10.3322/canjclin.42.2.74 10.1111/j.1445-2197.2012.06257.x 10.1007/s00261-010-9648-y 10.1097/00000478-198006000-00014 10.1016/S1386-6346(02)00014-1 10.1016/S0041-1345(02)03563-7 10.1002/dc.2011 10.1097/00004728-199401000-00036 10.1007/s00595-006-3204-y 10.1002/jmri.21519 10.1080/136518201753173692 10.1186/s12893-019-0598-1 10.1007/BF00196156 |
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Title | Primary leiomyoma of the liver in an immunocompetent patient |
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