Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope - Zafar, Atif; Wang, Wei; Liu, Gang; Xian, Wa; McKeon, Frank; Zhou, Jia; Zhang, Ruiwen (Cancer letters, 2021)
Keywords: Animals; Antineoplastic Agents - therapeutic use; Apoptosis; Biology; Cancer therapies; Cell cycle; Clinical trials; Deoxyribonucleic acid; DNA; DNA damage; Drug resistance; Gene amplification; Gene Expression Regulation, Neoplastic - drug effects; Genomes; Genomic instability; Humans; Inhibitors; MDM2; MDM2 protein; Medical prognosis; Molecular Targeted Therapy; Mutation; Mutation rates; Neuroblastoma; Neuroblastoma - drug therapy; Neuroblastoma - metabolism; Neuroblastoma - pathology; Oncology; p53; p53 Protein; Proteins; Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors; Signal transduction; Targeted therapy; Transcription; Tumor Suppressor Protein p53 - antagonists & inhibitors; Tumors; Vascular endothelial growth factor; MDM2; Inhibitors; Neuroblastoma; Targeted therapy; p53