Investigating the tradeoffs between spatial resolution and diffusion sampling for brain mapping with diffusion tractography: Time well spent?

• Published in: Human brain mapping Vol. 35; no. 11; pp. 5667 - 5685
• Main Authors: Calabrese, Evan, Badea, Alexandra, Coe, Christopher L., Lubach, Gabriele R., Styner, Martin A., Johnson, G. Allan
• Format: Journal Article
• Language: English
• Published: New York, NY Blackwell Publishing Ltd 01.11.2014; Wiley-Liss; John Wiley & Sons, Inc; John Wiley and Sons Inc
• Subjects: Algorithms; Animals; Biological and medical sciences; Brain - anatomy & histology; Brain Mapping; Computer Simulation; connectome; diffusion magnetic resonance imaging; Diffusion Tensor Imaging; Electrocardiography. Vectocardiography; Electrodiagnosis. Electric activity recording; Image Processing, Computer-Assisted; Investigative techniques, diagnostic techniques (general aspects); Macaca mulatta; Medical sciences; Models, Neurological; Nervous system; Neural Pathways - anatomy & histology; Neural Pathways - physiology; neuroanatomy; Primates; Radiodiagnosis. Nmr imagery. Nmr spectrometry; White Matter - anatomy & histology; Cartography; Nervous system diseases; diffusion magnetic resonance imaging; Radiodiagnosis; Tractography; Central nervous system; Samplings; Diffusion imaging; Macaca mulatta; Nuclear magnetic resonance imaging; Encephalon; Diffusion tensor imaging; Vertebrata; Mammalia; Primates; Simioidea; connectome; neuroanatomy; Diffusion; Sampling; Spatial resolution; diffusion tensor imaging

Interest in mapping white matter pathways in the brain has peaked with the recognition that altered brain connectivity may contribute to a variety of neurologic and psychiatric diseases. Diffusion tractography has emerged as a popular method for postmortem brain mapping initiatives, including the ex...