Association between HLA‐B1502 Allele and Antiepileptic Drug‐Induced Cutaneous Reactions in Han Chinese - Man, Celeste B.L.; Kwan, Patrick; Baum, Larry; Yu, Evelyn; Lau, K.M.; Cheng, Alice S.H.; Ng, Margaret H.L. (Epilepsia (Copenhagen), 2007)
Keywords: Adolescent; Adult; Alleles; Anticonvulsants - adverse effects; Anticonvulsants - therapeutic use; Anticonvulsants. Antiepileptics. Antiparkinson agents; Antiepileptic drugs; Asian Continental Ancestry Group - genetics; Biological and medical sciences; Carbamazepine - adverse effects; Carbamazepine - therapeutic use; Case-Control Studies; Child; Cutaneous reactions; Drug Eruptions - ethnology; Drug Eruptions - etiology; Drug Eruptions - genetics; Drug Hypersensitivity - ethnology; Drug Hypersensitivity - genetics; Drug toxicity and drugs side effects treatment; Epilepsy - drug therapy; Epilepsy - ethnology; Epilepsy - genetics; Female; Genetic Predisposition to Disease - ethnology; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; HLA; HLA-B Antigens - genetics; HLA-B15 Antigen; Hong Kong; Humans; Male; Medical sciences; Middle Aged; Miscellaneous (drug allergy, mutagens, teratogens...); Nervous system (semeiology, syndromes); Neurology; Neuropharmacology; Pharmacogenetics; Pharmacology. Drug treatments; Phenytoin - adverse effects; Phenytoin - therapeutic use; Polymorphism, Genetic; Rash; Stevens-Johnson Syndrome - chemically induced; Stevens-Johnson Syndrome - ethnology; Stevens-Johnson Syndrome - genetics; Stevens‐Johnson syndrome; Triazines - adverse effects; Triazines - therapeutic use; Hong Kong; Bullous dermatosis; HLA-System; HLA-Cutaneous reactions-Antiepileptic drugs-Rash-Stevens-Johnson syndrome; Eye disease; Skin disease; Nervous system diseases; Stomatology; Epilepsy; Central nervous system disease; Anticonvulsant; Stevens Johnson syndrome; Cerebral disorder