Plasma and mucosal HIV viral loads are associated with genital tract inflammation in HIV-infected women

• Published in: Journal of acquired immune deficiency syndromes (1999) Vol. 63; no. 4; p. 485
• Main Authors: Herold, Betsy C, Keller, Marla J, Shi, Qiuhu, Hoover, Donald R, Carpenter, Colleen A, Huber, Ashley, Parikh, Urvi M, Agnew, Kathy J, Minkoff, Howard, Colie, Christine, Nowicki, Marek J, DʼSouza, Gypsyamber, Watts, D Heather, Anastos, Kathryn
• Format: Journal Article
• Language: English
• Published: United States 01.08.2013
• Subjects: Adult; Anti-Retroviral Agents - therapeutic use; Case-Control Studies; CD4 Lymphocyte Count; Cervix Uteri; Chemokines - metabolism; Cross-Sectional Studies; Cytokines - blood; Cytokines - metabolism; Escherichia coli - growth & development; Female; HIV Infections - complications; HIV Infections - immunology; HIV Infections - virology; Humans; Middle Aged; Mucous Membrane - metabolism; Mucous Membrane - virology; RNA, Viral - blood; Uterine Cervicitis - metabolism; Uterine Cervicitis - virology; Vagina; Vaginal Douching; Vaginitis - metabolism; Vaginitis - virology; Viral Load; Virus Shedding

Systemic and mucosal inflammation may play a role in HIV control. A cross-sectional comparison was conducted among women in the Women's Interagency HIV Study to explore the hypothesis that compared with HIV-uninfected participants, women with HIV, and, in particular, those with high plasma vira...