LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants

• Published in: Bioinformatics Vol. 31; no. 21; pp. 3555 - 3557
• Main Authors: Machiela, Mitchell J., Chanock, Stephen J.
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.11.2015
• Subjects: Alleles; Applications Notes; Bioinformatics; Chromosome Mapping; Genetic Predisposition to Disease; Haplotypes; Humans; Interactive; Internet; Joining; Linkage Disequilibrium; Linking; Modules; Polymorphism, Single Nucleotide; Population Groups - genetics; Populations; Query processing; Software; World Wide Web

Assessing linkage disequilibrium (LD) across ancestral populations is a powerful approach for investigating population-specific genetic structure as well as functionally mapping regions of disease susceptibility. Here, we present LDlink, a web-based collection of bioinformatic modules that query sin...