Dengue virus infection modifies mosquito blood-feeding behavior to increase transmission to the host

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 119; no. 3; pp. 1 - 9
• Main Authors: Xiang, Benjamin Wong Wei, Saron, Wilfried A. A., Stewart, James C., Hain, Arthur, Walvekar, Varsha, Missé, Dorothée, Thomas, Fréderic, Kini, R. Manjunatha, Roche, Benjamin, Claridge-Chang, Adam, St. John, Ashley L., Pompon, Julien
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 18.01.2022
• Series: From the Cover
• Subjects: Aedes - virology; Animal biology; Animals; Animals Behavior, Animal / physiology; Aquatic insects; Behavior; Behavior, Animal - physiology; Biological Sciences; Biting; Blood; Culicidae; Dengue - transmission; Dengue - virology; Dengue fever; Dengue Virus - physiology; Disease transmission; Ecology, environment; Epidemic models; Epidemiology; Feeding behavior; Feeding Behavior - physiology; Food and Nutrition; Host searching behavior; Host-Pathogen Interactions - physiology; Human health and pathology; Infections; Infectious diseases; Invertebrate Zoology; Life Sciences; Mathematical models; Mosquitoes; Multidisciplinary research; Multivariate Analysis; Santé publique et épidémiologie; Symbiosis; Vector-borne diseases; Viruses; epidemiology; transmission; blood-feeding behavior; dengue virus; mosquito; Dengue virus; Mosquito; Epidemiology; Blood-feeding behavior; Transmission

Mosquito blood-feeding behavior is a key determinant of the epidemiology of dengue viruses (DENV), the most-prevalent mosquitoborne viruses. However, despite its importance, how DENV infection influences mosquito blood-feeding and, consequently, transmission remains unclear. Here, we developed a hig...