Medulloblastoma—translating discoveries from the bench to the bedside

• Published in: Nature reviews. Clinical oncology Vol. 11; no. 12; pp. 714 - 722
• Main Authors: Gajjar, Amar J., Robinson, Giles W.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2014; Nature Publishing Group
• Subjects: 692/699/67/1922; 692/699/67/2332; 692/699/67/69; 692/700/1720; Adolescent; Brain Neoplasms - pathology; Brain Neoplasms - therapy; Care and treatment; Child; Child, Preschool; Development and progression; Distribution; Gene Expression Profiling; Humans; Infant; Medicine & Public Health; Medulloblastoma; Medulloblastoma - pathology; Medulloblastoma - therapy; Oncology; Prognosis; review-article

Key Points Medulloblastoma is a malignant brain tumour that occurs predominantly in childhood, but is also seen in infancy and throughout adulthood Although the prognosis of medulloblastoma is favourable with current therapeutic regimens, the heterogeneous nature of this cancer has confounded effort...