Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways - Happé, Hester; Leonhard, Wouter N.; van der Wal, Annemieke; van de Water, Bob; Lantinga-van Leeuwen, Irma S.; Breuning, Martijn H.; de Heer, Emile; Peters, Dorien J.M. (Human molecular genetics, 2009)
Keywords: Animals; Biological and medical sciences; Cell physiology; Cell Polarity; Cell Proliferation; Disease Models, Animal; Fundamental and applied biological sciences. Psychology; Gene Deletion; Genetics of eukaryotes. Biological and molecular evolution; Humans; Kidney Tubules - cytology; Kidney Tubules - injuries; Kidney Tubules - metabolism; Male; Mice; Mice, Knockout; Molecular and cellular biology; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Polycystic Kidney, Autosomal Dominant - genetics; Polycystic Kidney, Autosomal Dominant - metabolism; Polycystic Kidney, Autosomal Dominant - physiopathology; Signal Transduction; TRPP Cation Channels - genetics; TRPP Cation Channels - metabolism; Wnt Proteins - genetics; Wnt Proteins - metabolism; Chromosomal aberration; Signal transduction; Vertebrata; Mammalia; Urinary system; Mouse; Rodentia; Deletion; Genetics; Cell polarity; Kidney