Assessing the persistence, bioaccumulation potential and toxicity of brominated flame retardants: Data availability and quality for 36 alternative brominated flame retardants
Polybrominated diphenylethers (PBDEs) and hexabromocyclododecane (HBCDD) are major brominated flame retardants (BFRs) that are now banned or under restrictions in many countries because of their persistence, bioaccumulation potential and toxicity (PBT properties). However, there is a wide range of a...
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Published in | Chemosphere (Oxford) Vol. 116; pp. 118 - 123 |
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Main Authors | , , , |
Format | Journal Article Conference Proceeding |
Language | English |
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01.12.2014
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Abstract | Polybrominated diphenylethers (PBDEs) and hexabromocyclododecane (HBCDD) are major brominated flame retardants (BFRs) that are now banned or under restrictions in many countries because of their persistence, bioaccumulation potential and toxicity (PBT properties). However, there is a wide range of alternative BFRs, such as decabromodiphenyl ethane and tribromophenol, that are increasingly used as replacements, but which may possess similar hazardous properties. This necessitates hazard and risk assessments of these compounds. For a set of 36 alternative BFRs, we searched 25 databases for chemical property data that are needed as input for a PBT assessment. These properties are degradation half-life, bioconcentration factor (BCF), octanol–water partition coefficient (Kow), and toxic effect concentrations in aquatic organisms. For 17 of the 36 substances, no data at all were found for these properties. Too few persistence data were available to even assess the quality of these data in a systematic way. The available data for Kow and toxicity show surprisingly high variability, which makes it difficult to identify the most reliable values. We propose methods for systematic evaluations of PBT-related chemical property data that should be performed before data are included in publicly available databases. Using these methods, we evaluated the data for Kow and toxicity in more detail and identified several inaccurate values. For most of the 36 alternative BFRs, the amount and the quality of the PBT-related property data need to be improved before reliable hazard and risk assessments of these substances can be performed. |
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AbstractList | Polybrominated diphenylethers (PBDEs) and hexabromocyclododecane (HBCDD) are major brominated flame retardants (BFRs) that are now banned or under restrictions in many countries because of their persistence, bioaccumulation potential and toxicity (PBT properties). However, there is a wide range of alternative BFRs, such as decabromodiphenyl ethane and tribromophenol, that are increasingly used as replacements, but which may possess similar hazardous properties. This necessitates hazard and risk assessments of these compounds. For a set of 36 alternative BFRs, we searched 25 databases for chemical property data that are needed as input for a PBT assessment. These properties are degradation half-life, bioconcentration factor (BCF), octanol–water partition coefficient (Kow), and toxic effect concentrations in aquatic organisms. For 17 of the 36 substances, no data at all were found for these properties. Too few persistence data were available to even assess the quality of these data in a systematic way. The available data for Kow and toxicity show surprisingly high variability, which makes it difficult to identify the most reliable values. We propose methods for systematic evaluations of PBT-related chemical property data that should be performed before data are included in publicly available databases. Using these methods, we evaluated the data for Kow and toxicity in more detail and identified several inaccurate values. For most of the 36 alternative BFRs, the amount and the quality of the PBT-related property data need to be improved before reliable hazard and risk assessments of these substances can be performed. |
Author | Stieger, Greta Ng, Carla A. Scheringer, Martin Hungerbühler, Konrad |
Author_xml | – sequence: 1 givenname: Greta surname: Stieger fullname: Stieger, Greta – sequence: 2 givenname: Martin surname: Scheringer fullname: Scheringer, Martin email: scheringer@chem.ethz.ch – sequence: 3 givenname: Carla A. surname: Ng fullname: Ng, Carla A. – sequence: 4 givenname: Konrad surname: Hungerbühler fullname: Hungerbühler, Konrad |
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Cites_doi | 10.1021/es3002713 10.1021/es015848h 10.1897/03-279 10.1016/j.envint.2010.11.007 10.1016/j.envint.2012.08.003 10.1002/etc.5620110705 10.1016/0300-483X(81)90130-X 10.1897/06-142R.1 10.1002/jps.2600840120 10.1021/es0351591 10.1002/jps.2600820804 10.1016/B978-0-12-386454-3.00551-0 10.1021/es0502526 10.1016/j.scitotenv.2011.12.035 10.1016/j.aquatox.2010.01.007 10.1139/f83-096 |
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Keywords | PBT assessment Octanol–water partition coefficient Baseline toxicity Brominated flame retardants Availability Ecotoxicology Database query Pollutant behavior Toxicity Octanol-water partition coefficient Octanol Flame retardant Partition coefficient Persistence Aquatic environment Quality Bromine Organic compounds Phase partition Biological accumulation Lipophilicity Physicochemical properties |
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References | Escher, Hermens (b0030) 2002; 36 Veith, Call, Brooke (b0100) 1983; 40 EPA, 2013. High Production Volume Information System. US Environmenal Protection Agency, Washington DC Meylan, Howard (b0060) 1995; 84 Verhaar, H.J.M., Mulder, W., Hermens, J.L.M., Rorije, E., Langenberg, J.H., Peijnenburg, W.J.G.M., et al. 1995. Overview of structure-activity relationships for environmental endpoints, Part 1. Report of the EU-DG-XII Project QSAR for predicting fate and effects of chemicals in the environment. Schenker, MacLeod, Scheringer, Hungerbühler (b0070) 2005; 39 Pontolillo, Eganhouse (b0065) 2001 . Könemann (b0035) 1981; 19 Maeder, Escher, Scheringer, Hungerbühler (b0045) 2004; 38 Sotomatsu, Shigemura, Murata, Fujita (b0085) 1993; 82 Strempel, Scheringer, Ng, Hungerbühler (b0090) 2012; 46 He, Luo, Chen, Sun, Chen, Mai (b0115) 2012; 419 Smith, Dom, Blust, Mayer (b0080) 2010; 98 Kuramochi, Maeda, Kawamoto (b0040) 2004; 23 Mayer, Reichenberg (b0050) 2006; 25 UNEP (2013) Stockholm convention on persistent organic pollutants. WHO, 2005 (b0110) 2005 Bergman, Rydén, Law, de Boer, Covaci, Alaee (b0005) 2012; 49 Covaci, Harrad, Abdallah, Ali, Law, Herzke, de Wit (b0010) 2011; 37 ECHA, 2013b. Registered Substances. European Chemicals Agency, Helsinki McCarty, Mackay, Smith, Ozburn, Dixon (b0055) 1992; 11 ECHA, 2013a. Candidate list of Substances of Very High Concern for Authorisation. European Chemicals Agency, Helsinki Schwarzenbach, Gschwend, Imboden (b0075) 2003 Schwarzenbach (10.1016/j.chemosphere.2014.01.083_b0075) 2003 Covaci (10.1016/j.chemosphere.2014.01.083_b0010) 2011; 37 Smith (10.1016/j.chemosphere.2014.01.083_b0080) 2010; 98 Bergman (10.1016/j.chemosphere.2014.01.083_b0005) 2012; 49 10.1016/j.chemosphere.2014.01.083_b0015 10.1016/j.chemosphere.2014.01.083_b0025 He (10.1016/j.chemosphere.2014.01.083_b0115) 2012; 419 10.1016/j.chemosphere.2014.01.083_b0105 Strempel (10.1016/j.chemosphere.2014.01.083_b0090) 2012; 46 Veith (10.1016/j.chemosphere.2014.01.083_b0100) 1983; 40 Meylan (10.1016/j.chemosphere.2014.01.083_b0060) 1995; 84 WHO, 2005 (10.1016/j.chemosphere.2014.01.083_b0110) 2005 10.1016/j.chemosphere.2014.01.083_b0095 Escher (10.1016/j.chemosphere.2014.01.083_b0030) 2002; 36 Mayer (10.1016/j.chemosphere.2014.01.083_b0050) 2006; 25 Sotomatsu (10.1016/j.chemosphere.2014.01.083_b0085) 1993; 82 10.1016/j.chemosphere.2014.01.083_b0020 Maeder (10.1016/j.chemosphere.2014.01.083_b0045) 2004; 38 Kuramochi (10.1016/j.chemosphere.2014.01.083_b0040) 2004; 23 Schenker (10.1016/j.chemosphere.2014.01.083_b0070) 2005; 39 Pontolillo (10.1016/j.chemosphere.2014.01.083_b0065) 2001 Könemann (10.1016/j.chemosphere.2014.01.083_b0035) 1981; 19 McCarty (10.1016/j.chemosphere.2014.01.083_b0055) 1992; 11 |
References_xml | – volume: 419 start-page: 109 year: 2012 end-page: 115 ident: b0115 article-title: Bioaccumulation of polybrominated diphenyl ethers and decabromodiphenyl ethane in fish from a river system in a highly industrialized area, South China publication-title: Sci. Total Environ. contributor: fullname: Mai – volume: 84 start-page: 83 year: 1995 end-page: 92 ident: b0060 article-title: Atom/fragment contribution method for estimating octanol–water partition coefficients publication-title: J. Pharm. Sci. contributor: fullname: Howard – volume: 25 start-page: 2639 year: 2006 end-page: 2644 ident: b0050 article-title: Can highly hydrophobic organic substances cause aquatic baseline toxicity and can they contribute to mixture toxicity? publication-title: Environ. Toxicol. Chem. contributor: fullname: Reichenberg – volume: 46 start-page: 5680 year: 2012 end-page: 5687 ident: b0090 article-title: Screening for PBT chemicals among the “existing” and “new” chemicals of the EU publication-title: Environ. Sci. Technol. contributor: fullname: Hungerbühler – volume: 36 start-page: 4201 year: 2002 end-page: 4217 ident: b0030 article-title: Modes of action in ecotoxicology: their role in body burdens, species sensitivity, QSARs, and mixture effects publication-title: Environ. Sci. Technol. contributor: fullname: Hermens – volume: 19 start-page: 209 year: 1981 end-page: 221 ident: b0035 article-title: Quantitative structure-activity relationships in fish toxicity studies publication-title: Toxicol contributor: fullname: Könemann – year: 2001 ident: b0065 article-title: The search for reliable aqueous solubility (Sw) and octanol–water partition coefficient ( contributor: fullname: Eganhouse – volume: 98 start-page: 15 year: 2010 end-page: 24 ident: b0080 article-title: Controlling and maintaining exposure of hydrophobic organic compounds in aquatic toxicity tests by passive dosing publication-title: Aquat. Toxicol. contributor: fullname: Mayer – volume: 82 start-page: 776 year: 1993 end-page: 781 ident: b0085 article-title: Octanol–water partition coefficient of ortho-substituted aromatic solutes publication-title: J. Pharm. Sci. contributor: fullname: Fujita – volume: 39 start-page: 8434 year: 2005 end-page: 8441 ident: b0070 article-title: Improving data quality for environmental fate models: a least-squares adjustment procedure for harmonizing physicochemical properties of organic compounds publication-title: Environ. Sci. Technol. contributor: fullname: Hungerbühler – year: 2003 ident: b0075 article-title: Environmental Organic Chemistry contributor: fullname: Imboden – volume: 49 start-page: 57 year: 2012 end-page: 82 ident: b0005 article-title: A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals publication-title: Environ. Int. contributor: fullname: Alaee – year: 2005 ident: b0110 publication-title: Concise International Chemical Assessment Document 66 contributor: fullname: WHO, 2005 – volume: 40 start-page: 743 year: 1983 end-page: 748 ident: b0100 article-title: Structure-toxicity relationships for the fathead minnow, Pimephales promelas: narcotic industrial chemicals publication-title: Can. J. Fish. Aquat. Sci. contributor: fullname: Brooke – volume: 38 start-page: 3659 year: 2004 end-page: 3666 ident: b0045 article-title: Toxic ratio as an indicator of the intrinsic toxicity in the assessment of persistent, bioaccumulative, and toxic chemicals publication-title: Environ. Sci. Technol. contributor: fullname: Hungerbühler – volume: 23 start-page: 1386 year: 2004 end-page: 1393 ident: b0040 article-title: Water solubility and partitioning behavior of brominated phenols publication-title: Environ. Toxicol. Chem. contributor: fullname: Kawamoto – volume: 37 start-page: 532 year: 2011 end-page: 556 ident: b0010 article-title: Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour publication-title: Environ. Int. contributor: fullname: de Wit – volume: 11 start-page: 917 year: 1992 end-page: 930 ident: b0055 article-title: Residue-based interpretation of toxicity and bioconcentration QSARs from aquatic bioassays: neutral narcotic organics publication-title: Environ. Toxicol. Chem. contributor: fullname: Dixon – year: 2005 ident: 10.1016/j.chemosphere.2014.01.083_b0110 contributor: fullname: WHO, 2005 – ident: 10.1016/j.chemosphere.2014.01.083_b0015 – volume: 46 start-page: 5680 year: 2012 ident: 10.1016/j.chemosphere.2014.01.083_b0090 article-title: Screening for PBT chemicals among the “existing” and “new” chemicals of the EU publication-title: Environ. Sci. Technol. doi: 10.1021/es3002713 contributor: fullname: Strempel – volume: 36 start-page: 4201 year: 2002 ident: 10.1016/j.chemosphere.2014.01.083_b0030 article-title: Modes of action in ecotoxicology: their role in body burdens, species sensitivity, QSARs, and mixture effects publication-title: Environ. Sci. Technol. doi: 10.1021/es015848h contributor: fullname: Escher – volume: 23 start-page: 1386 year: 2004 ident: 10.1016/j.chemosphere.2014.01.083_b0040 article-title: Water solubility and partitioning behavior of brominated phenols publication-title: Environ. Toxicol. Chem. doi: 10.1897/03-279 contributor: fullname: Kuramochi – ident: 10.1016/j.chemosphere.2014.01.083_b0105 – volume: 37 start-page: 532 year: 2011 ident: 10.1016/j.chemosphere.2014.01.083_b0010 article-title: Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour publication-title: Environ. Int. doi: 10.1016/j.envint.2010.11.007 contributor: fullname: Covaci – volume: 49 start-page: 57 year: 2012 ident: 10.1016/j.chemosphere.2014.01.083_b0005 article-title: A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals publication-title: Environ. Int. doi: 10.1016/j.envint.2012.08.003 contributor: fullname: Bergman – ident: 10.1016/j.chemosphere.2014.01.083_b0025 – volume: 11 start-page: 917 year: 1992 ident: 10.1016/j.chemosphere.2014.01.083_b0055 article-title: Residue-based interpretation of toxicity and bioconcentration QSARs from aquatic bioassays: neutral narcotic organics publication-title: Environ. Toxicol. Chem. doi: 10.1002/etc.5620110705 contributor: fullname: McCarty – volume: 19 start-page: 209 year: 1981 ident: 10.1016/j.chemosphere.2014.01.083_b0035 article-title: Quantitative structure-activity relationships in fish toxicity studies publication-title: Toxicol doi: 10.1016/0300-483X(81)90130-X contributor: fullname: Könemann – year: 2003 ident: 10.1016/j.chemosphere.2014.01.083_b0075 contributor: fullname: Schwarzenbach – volume: 25 start-page: 2639 year: 2006 ident: 10.1016/j.chemosphere.2014.01.083_b0050 article-title: Can highly hydrophobic organic substances cause aquatic baseline toxicity and can they contribute to mixture toxicity? publication-title: Environ. Toxicol. Chem. doi: 10.1897/06-142R.1 contributor: fullname: Mayer – volume: 84 start-page: 83 year: 1995 ident: 10.1016/j.chemosphere.2014.01.083_b0060 article-title: Atom/fragment contribution method for estimating octanol–water partition coefficients publication-title: J. Pharm. Sci. doi: 10.1002/jps.2600840120 contributor: fullname: Meylan – year: 2001 ident: 10.1016/j.chemosphere.2014.01.083_b0065 contributor: fullname: Pontolillo – volume: 38 start-page: 3659 year: 2004 ident: 10.1016/j.chemosphere.2014.01.083_b0045 article-title: Toxic ratio as an indicator of the intrinsic toxicity in the assessment of persistent, bioaccumulative, and toxic chemicals publication-title: Environ. Sci. Technol. doi: 10.1021/es0351591 contributor: fullname: Maeder – volume: 82 start-page: 776 year: 1993 ident: 10.1016/j.chemosphere.2014.01.083_b0085 article-title: Octanol–water partition coefficient of ortho-substituted aromatic solutes publication-title: J. Pharm. Sci. doi: 10.1002/jps.2600820804 contributor: fullname: Sotomatsu – ident: 10.1016/j.chemosphere.2014.01.083_b0095 – ident: 10.1016/j.chemosphere.2014.01.083_b0020 doi: 10.1016/B978-0-12-386454-3.00551-0 – volume: 39 start-page: 8434 year: 2005 ident: 10.1016/j.chemosphere.2014.01.083_b0070 article-title: Improving data quality for environmental fate models: a least-squares adjustment procedure for harmonizing physicochemical properties of organic compounds publication-title: Environ. Sci. Technol. doi: 10.1021/es0502526 contributor: fullname: Schenker – volume: 419 start-page: 109 year: 2012 ident: 10.1016/j.chemosphere.2014.01.083_b0115 article-title: Bioaccumulation of polybrominated diphenyl ethers and decabromodiphenyl ethane in fish from a river system in a highly industrialized area, South China publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2011.12.035 contributor: fullname: He – volume: 98 start-page: 15 year: 2010 ident: 10.1016/j.chemosphere.2014.01.083_b0080 article-title: Controlling and maintaining exposure of hydrophobic organic compounds in aquatic toxicity tests by passive dosing publication-title: Aquat. Toxicol. doi: 10.1016/j.aquatox.2010.01.007 contributor: fullname: Smith – volume: 40 start-page: 743 year: 1983 ident: 10.1016/j.chemosphere.2014.01.083_b0100 article-title: Structure-toxicity relationships for the fathead minnow, Pimephales promelas: narcotic industrial chemicals publication-title: Can. J. Fish. Aquat. Sci. doi: 10.1139/f83-096 contributor: fullname: Veith |
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Snippet | Polybrominated diphenylethers (PBDEs) and hexabromocyclododecane (HBCDD) are major brominated flame retardants (BFRs) that are now banned or under restrictions... |
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SubjectTerms | 1-Octanol - chemistry Animal, plant and microbial ecology Animals Applied ecology Applied sciences Aquatic Organisms Baseline toxicity Biological and medical sciences Brominated flame retardants Ecotoxicology, biological effects of pollution Environmental Pollutants - analysis Environmental Pollutants - chemistry Environmental Pollutants - toxicity Exact sciences and technology Flame Retardants - analysis Flame Retardants - toxicity Fundamental and applied biological sciences. Psychology General aspects Global environmental pollution Half-Life Hydrocarbons, Aromatic - analysis Hydrocarbons, Aromatic - chemistry Hydrocarbons, Aromatic - toxicity Hydrocarbons, Brominated - analysis Hydrocarbons, Brominated - chemistry Hydrocarbons, Brominated - toxicity Octanol–water partition coefficient PBT assessment Pollution Risk Assessment Water - chemistry |
Title | Assessing the persistence, bioaccumulation potential and toxicity of brominated flame retardants: Data availability and quality for 36 alternative brominated flame retardants |
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