AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise

• Published in: Diabetes (New York, N.Y.) Vol. 50; no. 5; pp. 921 - 927
• Main Authors: Musi, Nicolas, Fujii, Nobuharu, Hirshman, Michael F., Ekberg, Ingvar, Fröberg, Sven, Ljungqvist, Olle, Thorell, Anders, Goodyear, Laurie J.
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.05.2001
• Subjects: AMP-Activated Protein Kinases; Biological and medical sciences; Blood Glucose - metabolism; Diabetes; Diabetes Mellitus, Type 2 - enzymology; Diabetes Mellitus, Type 2 - physiopathology; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Enzyme Activation; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Exercise; Exercise - physiology; Gene Expression Regulation, Enzymologic; Glucose; Glucose Transporter Type 4; Glycated Hemoglobin A - analysis; Glycogen - metabolism; Health aspects; Humans; Insulin; Kinases; Kinetics; Male; Medical sciences; Middle Aged; Monosaccharide Transport Proteins - metabolism; Multienzyme Complexes - genetics; Multienzyme Complexes - metabolism; Muscle Proteins; Muscle, Skeletal - metabolism; Muscle, Skeletal - physiology; Muscle, Skeletal - physiopathology; Musculoskeletal system; Phosphorylation; Physical Exertion - physiology; Physiological aspects; Protein kinases; Protein-Serine-Threonine Kinases - genetics; Protein-Serine-Threonine Kinases - metabolism; Proteins; Reference Values; Rest - physiology; RNA, Messenger - genetics; Transcription, Genetic; Type 2 diabetes; Workloads; United States; Endocrinopathy; Physical exercise; Human; Enzymatic activity; Enzyme; Transferases; Bicycle ergometer; Striated muscle; Non insulin dependent diabetes

AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise Nicolas Musi 1 , Nobuharu Fujii 1 , Michael F. Hirshman 1 , Ingvar Ekberg 2 , Sven Fröberg 2 , Olle Ljungqvist 2 3 , Anders Thorell 2 and Laurie J. Goodyear 1 1 Research Division, Joslin Diabe...