High-throughput miRNA sequencing and identification of biomarkers for forensically relevant biological fluids

• Published in: Electrophoresis Vol. 37; no. 21; pp. 2780 - 2788
• Main Authors: Seashols-Williams, Sarah, Lewis, Carolyn, Calloway, Chelsea, Peace, Nerissa, Harrison, Ariana, Hayes-Nash, Christina, Fleming, Samantha, Wu, Qianni, Zehner, Zendra E.
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 01.10.2016
• Subjects: Bacteria; biomarkers; Blood; Body fluid identification; Body fluids; Body Fluids - chemistry; electrophoresis; feces; Female; Fluids; Forensic Genetics - methods; Forensic science; forensic sciences; Genetic Markers - genetics; High throughput sequencing; high-throughput nucleotide sequencing; High-Throughput Nucleotide Sequencing - methods; Humans; lipids; Male; microbial load; microRNA; MicroRNAs - analysis; MicroRNAs - genetics; non-coding RNA; Proteins; Ribonucleic acids; Saliva; semen; Sequence Analysis, RNA - methods; Sequencing; Serology; translation (genetics); urine; microRNA; Serology; Forensic science; High throughput sequencing; Body fluid identification
• ISSN: 0173-0835; 1522-2683; 1522-2683
• DOI: 10.1002/elps.201600258

microRNAs (miRNAs) are small noncoding RNAs that regulate cellular processes through modulation of proteins at the translational level. They tend to be highly stable as compared to other RNA species due to their small size and protection by protein and/or lipid matrices. Thus, it is likely that miRN...