Genetic polymorphisms in innate immunity genes influence predisposition to tick-borne encephalitis

• Published in: Journal of NeuroVirology Vol. 29; no. 6; pp. 699 - 705
• Main Authors: Fortova, Andrea, Barkhash, Andrey V., Pychova, Martina, Krbkova, Lenka, Palus, Martin, Salat, Jiri, Ruzek, Daniel
• Format: Journal Article
• Language: English
• Published: Cham Springer Science and Business Media LLC 01.12.2023; Springer International Publishing
• Subjects: Biomedical and Life Sciences; Biomedicine; Encephalitis Viruses, Tick-Borne - genetics; Encephalitis, Tick-Borne - epidemiology; Encephalitis, Tick-Borne - genetics; Genotype; Humans; Immunity, Innate - genetics; Immunology; Infectious Diseases; Interferons - genetics; Neurology; Neurosciences; Polymorphism, Single Nucleotide; Tick-borne encephalitis; Genetics; Immunity genes; Single-nucleotide polymorphism; Predisposition; Virology; Genetics; Single-nucleotide polymorphism; Immunity genes; Tick-borne encephalitis; Predisposition

Tick-borne encephalitis (TBE) is a neuroviral disease that ranges in severity from a mild febrile illness to a severe and life-threatening meningoencephalitis or encephalomyelitis. There is increasing evidence that susceptibility to tick-borne encephalitis virus (TBEV)-induced disease and its severi...