Human dorsal-root-ganglion perfusion measured in-vivo by MRI

• Published in: NeuroImage (Orlando, Fla.) Vol. 141; pp. 81 - 87
• Main Authors: Godel, Tim, Pham, Mirko, Heiland, Sabine, Bendszus, Martin, Bäumer, Philipp
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2016; Elsevier Limited
• Subjects: Blood; Blood Flow Velocity - physiology; Capillary Permeability - physiology; Cell body; DCE-MRI; Dorsal root ganglia; Female; Ganglia; Ganglia, Spinal - blood supply; Ganglia, Spinal - physiology; Humans; Image Interpretation, Computer-Assisted - methods; Leakage; Localization; Magnetic Resonance Angiography - methods; Magnetic resonance imaging; Male; Mathematical models; Metabolism; Metabolites; Middle Aged; Nervous system; Pain; Parameter estimation; Pelvis; Perfusion; Peripheral neuropathy; Permeability; Physiology; Polyneuropathy; Reproducibility of Results; Sacrum; Sensitivity and Specificity; Sex Factors; Spatial distribution; Spinal nerves; Statistical analysis; Vertebrae; NFRA; DCE-MRI; ESS; DCE; Permeability; Polyneuropathy; ROI; CBRA; Dorsal root ganglia; PNS; Perfusion; DRG; VIBE; AIF

To develop an in-vivo imaging method for the measurement of dorsal-root-ganglia-(DRG) perfusion, to establish its normal values in patients without known peripheral nerve disorders or radicular pain syndromes and to determine the physiological spatial perfusion pattern within the DRG. This prospecti...