Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy - Lee, Pei-Chi; Zan, Bo-Shen; Chen, Li-Ting; Chung, Tze-Wen (International journal of nanomedicine, 2019)
Keywords: Amines - chemistry; Animals; anticoagulant; Anticoagulants; Anticoagulants (Medicine); Anticoagulants - pharmacology; antioxidant; Antioxidants; Antioxidants - pharmacology; Biomedical materials; Blood clot; Cell Hypoxia - drug effects; Cell Line; Delayed-Action Preparations - pharmacology; Drug Delivery Systems; Drug Liberation; Drugs; Glutathione; Glutathione - chemistry; heparin; human bone marrow mesenchymal stem cells (hBMSCs); Human Umbilical Vein Endothelial Cells - drug effects; Humans; Hyaluronic acid; Hyaluronic Acid - chemistry; Hydrogen Peroxide - metabolism; Injuries; Ischemia; ischemia/reperfusion (I/R); Mesenchymal Stem Cells - drug effects; Mesenchymal Stem Cells - metabolism; Mice; Nanoparticles; Nanoparticles - chemistry; Nanoparticles - ultrastructure; Original Research; Oxidative stress; Polylactic Acid-Polyglycolic Acid Copolymer - chemistry; Scientific equipment and supplies industry; Stem cells; Superoxides - metabolism; Thrombosis; Tissue engineering; Transplantation; Vehicles; United States; Germany; Taiwan; heparin; antioxidant; glutathione; human bone marrow mesenchymal stem cells; anticoagulant; I/R; reperfusion; hBMSCs; ischemia