X-Ray Luminescence Computed Tomography via Selective Excitation: A Feasibility Study

• Published in: IEEE transactions on medical imaging Vol. 29; no. 12; pp. 1992 - 1999
• Main Authors: Pratx, Guillem, Carpenter, Colin M, Sun, Conroy, Lei Xing
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.12.2010; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Algorithms; Biomedical optical imaging; Computed tomography; Computer Simulation; Feasibility Studies; Image Processing, Computer-Assisted - methods; Laboratory animals; Luminescence; Luminescent Measurements - methods; Medical imaging; Models, Theoretical; Molecular Imaging; Monte Carlo Method; Nanoparticles; Nanoparticles - chemistry; nanophosphor; optical imaging; Optical scattering; Optical sensors; Phantoms, Imaging; Spatial resolution; Tomography; Tomography, X-Ray Computed - methods; X-ray computed tomography (CT); X-ray detection; X-ray detectors; X-ray imaging; X-rays

X-ray luminescence computed tomography (XLCT) is proposed as a new molecular imaging modality based on the selective excitation and optical detection of X-ray-excitable phosphor nanoparticles. These nano-sized particles can be fabricated to emit near-infrared (NIR) light when excited with X-rays, an...