Ferroportin 3 is a dual‐targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis

• Published in: The Plant journal : for cell and molecular biology Vol. 107; no. 1; pp. 215 - 236
• Main Authors: Kim, Leah J., Tsuyuki, Kaitlyn M., Hu, Fengling, Park, Emily Y., Zhang, Jingwen, Iraheta, Jennifer G., Chia, Ju‐Chen, Huang, Rong, Tucker, Avery E., Clyne, Madeline, Castellano, Claire, Kim, Angie, Chung, Daniel D., DaVeiga, Christopher T., Parsons, Elizabeth M., Vatamaniuk, Olena K., Jeong, Jeeyon
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.07.2021
• Subjects: Amino Acid Sequence; Arabidopsis; Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; atomic absorption spectrometry; Cation Transport Proteins - genetics; Cation Transport Proteins - metabolism; chloroplast; Chloroplasts; Chloroplasts - metabolism; Conserved Sequence; ferroportin; Gene expression; Gene Expression Regulation, Plant; Homeostasis; Inductively coupled plasma mass spectrometry; Iron; Iron - metabolism; Iron deficiency; Mass spectrometry; Mass spectroscopy; Mitochondria; Mitochondria - genetics; Mitochondria - metabolism; Mitochondria - pathology; Mutants; Mutation; Nutrient deficiency; Organelles; Oxidative stress; Plant Roots - genetics; Plant Roots - metabolism; Plants, Genetically Modified; Shoots; transport; Ultrastructure; Yeasts - genetics; Yeasts - metabolism; iron; ferroportin; transport; chloroplast; Arabidopsis; mitochondria

Summary Mitochondria and chloroplasts are organelles with high iron demand that are particularly susceptible to iron‐induced oxidative stress. Despite the necessity of strict iron regulation in these organelles, much remains unknown about mitochondrial and chloroplast iron transport in plants. Here,...