Association of serum fibroblast growth factor 23 (FGF23) and incident fractures in older men: The Osteoporotic Fractures in Men (MrOS) study

• Published in: Journal of bone and mineral research Vol. 28; no. 11; pp. 2325 - 2332
• Main Authors: Lane, Nancy E, Parimi, Neeta, Corr, Maripat, Yao, Wei, Cauley, Jane A, Nielson, Carrie M, Ix, Joseph H, Kado, Deborah, Orwoll, Eric
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.11.2013
• Subjects: Aged; Demography; FGF23; Fibroblast Growth Factors - blood; Glomerular Filtration Rate; Humans; Incidence; Kidney - physiopathology; Male; MEN; OSTEOPOROSIS; Osteoporotic Fractures - blood; Osteoporotic Fractures - epidemiology; Osteoporotic Fractures - physiopathology; Risk Factors; FGF23; OSTEOPOROSIS; MEN

ABSTRACT Normal mineral metabolism is critical for skeletal integrity, and recently serum fibroblast growth factor 23 (FGF23) levels were found to be directly related to overall fracture risk in elderly Swedish men. To confirm this association, we performed a prospective case‐cohort study to underst...