Fasting and postprandial volumes of the undisturbed colon: normal values and changes in diarrhea‐predominant irritable bowel syndrome measured using serial MRI

• Published in: Neurogastroenterology and motility Vol. 26; no. 1; pp. 124 - 130
• Main Authors: Pritchard, S. E., Marciani, L., Garsed, K. C., Hoad, C. L., Thongborisute, W., Roberts, E., Gowland, P. A., Spiller, R. C.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2014; John Wiley & Sons Ltd
• Subjects: Adenylate cyclase; Adolescent; Adult; Colon; Colon - pathology; Colon - physiology; Diarrhea - diagnosis; Diarrhea - physiopathology; Fasting - physiology; Female; Humans; IBS‐D; Irritable Bowel Syndrome - diagnosis; Irritable Bowel Syndrome - physiopathology; Magnetic Resonance Imaging - methods; Magnetic Resonance Imaging - standards; Male; Middle Aged; MRI; Organ Size - physiology; Postprandial Period - physiology; Reference Values; volume; Young Adult; volume; IBS-D; Colon; MRI

Background Previous assessments of colon morphology have relied on tests which were either invasive or used ionizing radiation. We aimed to measure regional volumes of the undisturbed colon in healthy volunteers (HV) and patients with diarrhea‐predominant irritable bowel syndrome (IBS‐D). Methods 3D...