Gene tracing analysis reveals the contribution of neural crest‐derived cells in pituitary development

• Published in: Journal of anatomy Vol. 230; no. 3; pp. 373 - 380
• Main Authors: Ueharu, Hiroki, Yoshida, Saishu, Kikkawa, Takako, Kanno, Naoko, Higuchi, Masashi, Kato, Takako, Osumi, Noriko, Kato, Yukio
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2017; John Wiley and Sons Inc
• Subjects: Animals; Embryo, Mammalian; Immunohistochemistry; Mice; Mice, Transgenic; Models, Animal; Neural Crest - growth & development; neural crest cell; Organogenesis - physiology; Original; pituitary development; Pituitary Gland - embryology; PROP1; Rodents; SOX2; stem/progenitor cell; SOX2; pituitary development; PROP1; neural crest cell; stem/progenitor cell

The anterior pituitary originates from the adenohypophyseal placode. Both the preplacode region and neural crest (NC) derive from subdivision of the neural border region, and further individualization of the placode domain is established by a reciprocal interaction between placodal precursors and NC...