Development and validation of an age-sex-ethnicity-specific metabolic syndrome score in the Chinese adults

• Published in: Nature communications Vol. 14; no. 1; pp. 6988 - 14
• Main Authors: Yang, Shujuan, Yu, Bin, Yu, Wanqi, Dai, Shaoqing, Feng, Chuanteng, Shao, Ying, Zhao, Xing, Li, Xiaoqing, He, Tianjing, Jia, Peng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.11.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/163/2743/2037; 692/499; 692/699/2743/2037; Adult; Age; Blood Glucose - metabolism; Blood pressure; Body Mass Index; Body size; Cardiovascular diseases; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - epidemiology; Cholesterol; Cholesterol, HDL; Demographics; Demography; Diabetes mellitus; East Asian People; Ethnicity; Health risks; High density lipoprotein; Humanities and Social Sciences; Humans; Hyperlipidemia; Hypertension; Metabolic disorders; Metabolic Syndrome; Minority & ethnic groups; multidisciplinary; Risk assessment; Risk Factors; Science; Science (multidisciplinary); Sex; Subgroups; Sustainable development; Triglycerides; Uric Acid

Metabolic syndrome (MetS) is characterized by metabolic dysfunctions and could predict future risk for cardiovascular diseases (CVDs). However, the traditionally defined dichotomous MetS neither reflected MetS severity nor considered demographic variations. Here we develop a continuous, age-sex-ethn...