Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors - Yang, Dong; Duan, Mei-Han; Yuan, Qiu-Er; Li, Zhi-Ling; Luo, Chuang-Hua; Cui, Lan-Yue; Li, Li-Chao; Xiao, Ying; Zhu, Xian-Ying; Zhang, Hai-Liang; Feng, Gong-Kan; Liu, Guo-Chen; et al. (Journal of translational medicine, 2023)
Keywords: Analysis; Biomarkers; Care and treatment; Chemokines; Complications and side effects; Decision trees; Drug delivery; Fibroblasts; Gene expression; Immune checkpoint inhibitors; Immunosuppressive agents; Immunotherapy; Lymphocytes; Machine learning; Medical prognosis; Methods; Ovarian cancer; Platelet-derived growth factor; Prognostic signature; Regression analysis; Stroma; Tumor microenvironment; Tumors; Taiwan