The effect of Lu AG09222 on PACAP38- and VIP-induced vasodilation, heart rate increase, and headache in healthy subjects: an interventional, randomized, double-blind, parallel-group, placebo-controlled study - Rasmussen, Nadja Bredo; Deligianni, Christina; Christensen, Casper Emil; Karlsson, William Kristian; Al-Khazali, Haidar Muhsen; Van de Casteele, Tom; Granhall, Charlotte; Amin, Faisal Mohammad; Ashina, Messoud (Journal of headache and pain, 2023)
Keywords: Antibodies, Monoclonal, Humanized - therapeutic use; Arteries; Blood flow; Double-Blind Method; Double-blind studies; Headache; Headaches; Healthy Volunteers; Heart Rate; Humans; Internal Medicine; Medicine; Medicine & Public Health; Migraine; Migraine disorders; Migraine Disorders - therapy; Migraine treatment; Monoclonal antibodies; Monoclonal antibody; Neurology; Pain Medicine; Pituitary Adenylate Cyclase-Activating Polypeptide; Placebos; Vasoactive agents; Vasoactive Intestinal Peptide; Vasodilation; Pituitary adenylate cyclase-activating polypeptide; Migraine disorders; Monoclonal antibody; Migraine; Migraine treatment