A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer’s disease - Aron, Liviu; Qiu, Chenxi; Ngian, Zhen Kai; Liang, Marianna; Drake, Derek; Choi, Jaejoon; Fernandez, Marty A.; Roche, Perle; Bunting, Emma L.; Lacey, Ella K.; Hamplova, Sara E.; Yuan, Monlan; et al. (Nature communications, 2023)
Keywords: 13/106; 13/2; 42/44; 45/15; 45/41; 631/378/1689/1283; 631/378/2611; 64/60; Accumulation; Aging; Aging (artificial); Aging - metabolism; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer Disease - prevention & control; Alzheimer's disease; Amyloid; Amyloid beta-Peptides - metabolism; Animal models; Animals; Apoptosis; Cognitive ability; Cognitive Dysfunction - genetics; Cognitive Dysfunction - prevention & control; Deposition; Disease Models, Animal; Humanities and Social Sciences; Humans; Kinases; Mice; Mice, Transgenic; multidisciplinary; Neurodegeneration; Neurodegenerative diseases; Pathology; Protein folding; Proteins; Science; Science (multidisciplinary); Secretase; Tau protein; tau Proteins - metabolism; β-Amyloid; β-Catenin