Association between body fat distribution and B-lymphocyte subsets in peripheral blood

• Published in: Immunity & ageing Vol. 20; no. 1; pp. 1 - 9
• Main Authors: Prechtl, Pia, Schmitz, Timo, Pochert, Nicole, Traidl-Hoffmann, Claudia, Linseisen, Jakob, Meisinger, Christa, Freuer, Dennis
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 13.09.2023; BioMed Central; BMC
• Subjects: Adaptive immunity; Adipose tissue; Adipose tissues; Analysis; Anergy; Antibodies; B cells; B-lymphocytes; Body composition; Body fat; Body mass index; CD19 antigen; Cytokines; Estimates; Flow cytometry; Immune system; Immunoglobulin D; Immunoglobulin M; Immunological memory; Immunology; Inflammation; Lymphocytes; Lymphocytes B; Memory (Computers); Memory cells; Metabolic syndrome; Obesity; Peripheral blood; Phenotypes; Plasma; Visceral fat

Background Obesity is associated with chronic low-grade inflammation, which is underpinned by the presence of elevated levels of circulating proinflammatory cytokines in obese individuals. Due to the close relationship between adipose tissue and the immune system, it can be speculated that the accum...