Salmonella Typhimurium and inflammation: a pathogen-centric affair

• Published in: Nature reviews. Microbiology Vol. 19; no. 11; pp. 716 - 725
• Main Author: Galán, Jorge E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.11.2021; Nature Publishing Group
• Subjects: 631/250/254; 631/326/421; 631/326/88; Animals; Biomedical and Life Sciences; Coevolution; Development and progression; Epithelium; Homeostasis; Host-bacteria relationships; Host-Pathogen Interactions; Humans; Infectious Diseases; Inflammation; Inflammation - microbiology; Inflammation - pathology; Inflammatory response; Intestine; Life Sciences; Medical Microbiology; Microbiology; Microorganisms; Parasitology; Pathogens; Physiological aspects; Proteins; Receptors; Regulatory mechanisms (biology); Review Article; Salmonella; Salmonella enterica; Salmonella Infections - microbiology; Salmonella Infections - pathology; Salmonella typhimurium; Salmonella typhimurium - metabolism; Salmonellosis; Virology; United States

Microbial infections are controlled by host inflammatory responses that are initiated by innate immune receptors after recognition of conserved microbial products. As inflammation can also lead to disease, tissues that are exposed to microbial products such as the intestinal epithelium are subject t...