Gene-activated dermal equivalents to accelerate healing of diabetic chronic wounds by regulating inflammation and promoting angiogenesis

• Published in: Bioactive materials Vol. 5; no. 3; pp. 667 - 679
• Main Authors: Lou, Dong, Luo, Yu, Pang, Qian, Tan, Wei-Qiang, Ma, Lie
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.09.2020; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Angiogenesis; Diabetic chronic wounds; Gene-activated dermal equivalent; Inflammation; Vascular endothelial growth factor; Angiogenesis; Inflammation; Diabetic chronic wounds; Gene-activated dermal equivalent; Vascular endothelial growth factor

Diabetic chronic wound, characterized by prolonged inflammation and impaired angiogenesis, has become one of the most serious challenges in clinic and pose a significant healthcare burden worldwide. Although a great variety of wound dressings have been developed, few of encouraged achievements were...