Association of gene polymorphism of SDF1(CXCR12) with susceptibility to HIV-1 infection and AIDS disease progression: A meta-analysis

• Published in: PloS one Vol. 13; no. 2; p. e0191930
• Main Authors: Ding, Jiwei, Zhao, Jianyuan, Zhou, Jinming, Li, Xiaoyu, Wu, Yanbin, Ge, Mei, Cen, Shan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.02.2018; Public Library of Science (PLoS)
• Subjects: AIDS (Disease); Analysis; Biology and Life Sciences; Chemokine CXCL12 - genetics; Development and progression; Disease Progression; Disease susceptibility; Genetic aspects; Genetic polymorphisms; Genetic Predisposition to Disease; Health aspects; HIV infections; HIV Infections - genetics; HIV Infections - pathology; HIV-1; Humans; Medicine and Health Sciences; Physical Sciences; Physiological aspects; Polymorphism, Genetic; Publication Bias; Research and Analysis Methods; Risk factors; Science Policy; China

Genetic polymorphism of viral receptors is relevant to risks of HIV-1 infection, while it is still under debated whether the polymorphism of SDF1, a unique ligand for HIV-1 coreceptor CXCR4, is associated with HIV susceptibility and AIDS disease progression. Therefore, we provided an updated quantit...