Longitudinal viral shedding and antibody response characteristics of men with acute infection of monkeypox virus: a prospective cohort study

• Published in: Nature communications Vol. 15; no. 1; pp. 4488 - 12
• Main Authors: Yang, Yang, Niu, Shiyu, Shen, Chenguang, Yang, Liuqing, Song, Shuo, Peng, Yun, Xu, Yifan, Guo, Liping, Shen, Liang, Liao, Zhonghui, Liu, Jiexiang, Zhang, Shengjie, Cui, Yanxin, Chen, Jiayin, Chen, Si, Huang, Ting, Wang, Fuxiang, Lu, Hongzhou, Liu, Yingxia
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.05.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 45/23; 49/22; 631/326/2521; 631/326/596/1746; 692/699/255/2514; 82/1; Adult; Air conditioning; Antibodies; Antibodies, Neutralizing - blood; Antibodies, Neutralizing - immunology; Antibodies, Viral - blood; Antibodies, Viral - immunology; Antibody response; Coinfection - epidemiology; Coinfection - immunology; Coinfection - virology; Deoxyribonucleic acid; DNA; DNA, Viral; Fomites; Fomites - virology; HIV; HIV Infections - immunology; HIV Infections - virology; Human immunodeficiency virus; Humanities and Social Sciences; Humans; Immunoglobulin G; Infections; Lesions; Longitudinal Studies; Male; Middle Aged; Monkeypox virus - immunology; Mpox; Mpox, Monkeypox - epidemiology; Mpox, Monkeypox - immunology; Mpox, Monkeypox - virology; multidisciplinary; Neutralizing; Oropharynx; Oropharynx - immunology; Oropharynx - virology; Prospective Studies; Public health; Rectum; Saliva; Saliva - immunology; Saliva - virology; Science; Science (multidisciplinary); Skin; Skin diseases; Skin lesions; Viral Load; Virus Shedding; Viruses

Understanding of infection dynamics is important for public health measures against monkeypox virus (MPXV) infection. Herein, samples from multiple body sites and environmental fomites of 77 acute MPXV infections (HIV co-infection: N = 42) were collected every two to three days and used for detectio...