Anti-Parkinsonian drug discovery from herbal medicines: What have we got from neurotoxic models?

• Published in: Journal of ethnopharmacology Vol. 139; no. 3; pp. 698 - 711
• Main Authors: Song, Ju-Xian, Sze, Stephen Cho-Wing, Ng, Tzi-Bun, Lee, Caivin Kai-Fai, Leung, George P.H., Shaw, Pang-Chui, Tong, Yao, Zhang, Yan-Bo
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 15.02.2012
• Subjects: Animal models; Catechol; chemistry; China; Classification; Clinical trials; Curcumin; Drug Discovery; drug therapy; Flavonoids; ginsenosides; glycosides; Herbal medicines; Humans; India; Japan; Korean Peninsula; lignans; Models, Neurological; Movement disorders; Neurodegenerative diseases; Neuroprotection; Neurotoxicity; Neurotoxicity Syndromes; Neurotoxicity Syndromes - drug therapy; Neurotoxins; Parkinson disease; Parkinson Disease - drug therapy; Parkinson's disease; pathogenesis; phenylpropanoids; Phytotherapy; Plant Preparations; Plant Preparations - therapeutic use; Plants, Medicinal; Plants, Medicinal - chemistry; Resveratrol; Reviews; Signal transduction; Terpenes; terpenoids; therapeutic use; China; Japan; Korean Peninsula; India; Neuroprotection; Neurotoxins; Parkinson's disease; Herbal medicines

Herbal medicines are used to treat Parkinson's disease (PD) in ancient medical systems in Asian countries such as India, China, Japan and Korea based on their own anecdotal or experience-based theories. To systematically summarize and analyze the anti-Parkinsonian activities of herbal preparati...