UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer

• Published in: Oncology letters Vol. 9; no. 4; pp. 1567 - 1574
• Main Authors: GUAN, GE GE, WANG, WEN BO, LEI, BING XIN, WANG, QIAO LI, WU, LIN, FU, ZHEN MING, ZHOU, FU XIANG, ZHOU, YUN FENG
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.04.2015; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Analysis; Care and treatment; Cell cycle; Chemotherapy; Development and progression; Enzymes; Esophageal cancer; Gene expression; Genetic aspects; human telomerase reverse transcriptase; Medical prognosis; Metastasis; Mortality; Oncology; Physiological aspects; prognosis; Protein expression; Proteins; Radiation therapy; Risk factors; Telomerase; ubiquitin-conjugating enzyme E2D 3; China; esophageal cancer; ubiquitin-conjugating enzyme E2D 3; human telomerase reverse transcriptase; prognosis

Human telomerase reverse transcriptase (hTERT) is a critical factor in unlimited cell proliferation and immortalization, with numerous studies demonstrating that high expression of hTERT is a poor prognostic factor in various types of cancer. Ubiquitin-conjugating enzyme E2D 3 (UBE2D3) is a member o...