A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis

• Published in: Bioactive materials Vol. 20; pp. 271 - 285
• Main Authors: Li, Mengna, Xu, Jing-Wei, Li, Jiayong, Wang, Wei, Luo, Chenqi, Han, Haijie, Xu, Zhi-Kang, Yao, Ke
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.02.2023; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: 3D printing; Drug delivery intraocular lens; Gatifloxacin; Photocuring; Postoperative endophthalmitis; Drug delivery intraocular lens; Gatifloxacin; Postoperative endophthalmitis; 3D printing; Photocuring

Postoperative endophthalmitis (POE) has been the most threatening complication after cataract surgery, which perhaps can be solved by the antibiotic-loaded intraocular lens (IOL). However, most drug-loaded IOLs demonstrate insufficient drug quantity, short release time, increased implantation-relate...