Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine

• Published in: Scientific reports Vol. 13; no. 1; pp. 4687 - 11
• Main Authors: Xiao, Yongli, Beare, Paul A., Best, Sonja M., Morens, David M., Bloom, Marshall E., Taubenberger, Jeffery K.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.03.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326; 631/337; Animals; Coxiella burnetii; Deoxyribonucleic acid; DNA; Genomes; Humanities and Social Sciences; Infectious diseases; multidisciplinary; Next-generation sequencing; Pathogens; Phenols; Q fever; Rickettsia rickettsii; Rickettsia rickettsii - genetics; Rocky Mountain spotted fever; Rocky Mountain Spotted Fever - microbiology; Rocky Mountain Spotted Fever - prevention & control; Science; Science (multidisciplinary); Tick-borne diseases; Ticks - microbiology; Vaccines

Rocky Mountain spotted fever (RMSF) is a rapidly progressive and often fatal tick-borne disease caused by Rickettsia rickettsii . Its discovery and characterization by Howard Ricketts has been hailed as a remarkable historical example of detection and control of an emerging infectious disease, and s...