TPGS Decorated Liposomes as Multifunctional Nano-Delivery Systems

• Published in: Pharmaceutical research Vol. 40; no. 1; pp. 245 - 263
• Main Authors: Farooq, Muhammad Asim, Trevaskis, Natalie L.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2023; Springer; Springer Nature B.V
• Subjects: alpha-Tocopherol; Bioavailability; Biochemistry; Biocompatibility; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Drug delivery; Drug delivery systems; Drugs; Homeopathy; Humans; Liposomes; Materia medica and therapeutics; Medical Law; Nanoparticle Drug Delivery System; Neoplasms - drug therapy; Oral administration; Pharmacokinetics; Pharmacology/Toxicology; Pharmacy; Phospholipids; Polyethylene glycol; Polyethylene Glycols; Polyols; Review; Review Article; Solubilization; Surface active agents; Therapeutic applications; Therapeutics; Toxicity; Vehicles; Vincristine; Vitamin E; pharmacokinetics; cancer therapy; drug delivery; D-alpha-tocopheryl polyethylene glycol succinate (TPGS), liposomes

Liposomes are sphere-shaped vesicles that can capture therapeutics either in the outer phospholipid bilayer or inner aqueous core. Liposomes, especially when surface-modified with functional materials, have been used to achieve many benefits in drug delivery, including improving drug solubility, ora...