Reference values for low muscle mass and myosteatosis using tomographic muscle measurements in living kidney donors

• Published in: Scientific reports Vol. 13; no. 1; pp. 5835 - 8
• Main Authors: Westenberg, Lisa B., Zorgdrager, Marcel, Swaab, Tim D. A., van Londen, Marco, Bakker, Stephan J. L., Leuvenink, Henri G. D., Viddeleer, Alain R., Pol, Robert A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 10.04.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4022/272; 692/698/1671/1668/1973; 692/700/1421/1846/2771; Adult; Age; Body mass index; Computed tomography; Creatinine; Decision making; Female; Humanities and Social Sciences; Humans; Kidney Transplantation; Male; Middle Aged; multidisciplinary; Muscle, Skeletal - physiology; Musculoskeletal system; Organ donors; Quality control; Reference Values; Retrospective Studies; Sarcopenia - pathology; Science; Science (multidisciplinary); Skeletal muscle; Tomography, X-Ray Computed - methods; Vertebrae

Low muscle mass and myosteatosis are associated with poor clinical outcomes. Computed tomography (CT) imaging is an objective method for muscle mass and quality assessment; however consensus on cut-off values is lacking. This study assessed age-, sex-, and body mass index (BMI)-specific reference va...