Fanzor is a eukaryotic programmable RNA-guided endonuclease - Saito, Makoto; Xu, Peiyu; Faure, Guilhem; Maguire, Samantha; Kannan, Soumya; Altae-Tran, Han; Vo, Sam; Desimone, AnAn; Macrae, Rhiannon K.; Zhang, Feng (Nature (London), 2023)
Keywords: 42/44; 45/91; 631/45; 631/535; Adaptive immunity; Adaptive systems; Archaea; Archaea - genetics; Archaea - immunology; Bacteria; Bacteria - genetics; Bacteria - immunology; Biological activity; Chytridiomycota - enzymology; Complementarity; Conservation; Conserved Sequence; CRISPR; CRISPR-Associated Protein 9 - metabolism; CRISPR-Associated Proteins - chemistry; CRISPR-Associated Proteins - metabolism; CRISPR-Associated Proteins - ultrastructure; CRISPR-Cas Systems; Cryoelectron Microscopy; Deoxyribonucleic acid; DNA; DNA Transposable Elements - genetics; Electron microscopy; Endonuclease; Endonucleases - chemistry; Endonucleases - metabolism; Endonucleases - ultrastructure; Eukaryota - enzymology; Eukaryotes; Evolution, Molecular; Fungal Proteins - chemistry; Fungal Proteins - metabolism; Fungal Proteins - ultrastructure; Fungi; Gene Editing - methods; Gene sequencing; Genes; Genome editing; Genomes; Humanities and Social Sciences; Humans; multidisciplinary; Nucleic acids; Prokaryotes; Proteins; Ribonucleic acid; RNA; RNA - genetics; RNA - metabolism; RNA modification; RNA, Guide, CRISPR-Cas Systems - genetics; RNA, Guide, CRISPR-Cas Systems - metabolism; RNA-mediated interference; rRNA; Science; Science (multidisciplinary)