Safety pharmacology of acute LSD administration in healthy subjects

• Published in: Psychopharmacology Vol. 239; no. 6; pp. 1893 - 1905
• Main Authors: Holze, Friederike, Caluori, Toya V., Vizeli, Patrick, Liechti, Matthias E.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2022; Springer; Springer Nature B.V
• Subjects: Acute effects; Analysis; Anxiety; Biomedical and Life Sciences; Biomedicine; Blood pressure; Body temperature; Clinical trials; Cross-Over Studies; Dosage and administration; Double-Blind Method; Drug dosages; Hallucinogens - adverse effects; Healthy Volunteers; Heart Rate; Humans; Kidneys; Liver; LSD; LSD (Drug); Lysergic acid diethylamide; Lysergic Acid Diethylamide - adverse effects; Lysergide; Mental disorders; Neurosciences; Original Investigation; Pharmacology; Pharmacology/Toxicology; Physiological aspects; Psychiatry; Psychological aspects; Safety; Side effects; Switzerland; Heart rate; Flashback; Subjective effects; Blood pressure; Safety; Concentration; LSD

Rationale Lysergic acid diethylamide (LSD) is used in psychiatric and psychological research and investigated as a potential treatment for medical and psychiatric disorders, including depression, anxiety, and cluster headache. Objectives Safety data on clinical safety are available from small studie...