Peripheral Nerve Regeneration Using a Cytokine Cocktail Secreted by Skeletal Muscle-Derived Stem Cells in a Mouse Model

• Published in: Journal of clinical medicine Vol. 10; no. 4; p. 824
• Main Authors: Maki, Daisuke, Tamaki, Tetsuro, Fukuzawa, Tsuyoshi, Natsume, Toshiharu, Yamato, Ippei, Uchiyama, Yoshiyasu, Saito, Kosuke, Okami, Kenji
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 17.02.2021; MDPI
• Subjects: Analgesics; Clinical medicine; Collagen; Cytokines; facilitation effect; Musculoskeletal system; regenerative medicine; severe peripheral nerve injury; Stem cell transplantation; therapeutic adjunct; therapeutic agent; Japan; severe peripheral nerve injury; therapeutic agent; facilitation effect; regenerative medicine; therapeutic adjunct

Severe peripheral nerve injury, which does not promise natural healing, inevitably requires clinical treatment. Here, we demonstrated the facilitation effect of peripheral nerve regeneration using a cytokine cocktail secreted by skeletal muscle-derived stem cells (Sk-MSCs). Mouse sciatic nerve was t...