iPSC-derived cranial neural crest-like cells can replicate dental pulp tissue with the aid of angiogenic hydrogel

• Published in: Bioactive materials Vol. 14; pp. 290 - 301
• Main Authors: Kobayashi, Yoshifumi, Nouet, Julie, Baljinnyam, Erdenechimeg, Siddiqui, Zain, Fine, Daniel H., Fraidenraich, Diego, Kumar, Vivek A., Shimizu, Emi
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.08.2022; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Angiogenic self-assembling peptide hydrogel; Cranial neural crest; Fibroblast growth factor; iPSC; Odontoblastic differentiation; Regenerative endodontics; Fibroblast growth factor; Odontoblastic differentiation; Regenerative endodontics; Cranial neural crest; iPSC; Angiogenic self-assembling peptide hydrogel

The dental pulp has irreplaceable roles in maintaining healthy teeth and its regeneration is a primary aim of regenerative endodontics. This study aimed to replicate the characteristics of dental pulp tissue by using cranial neural crest (CNC)-like cells (CNCLCs); these cells were generated by modif...