Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: Results in 663 patients

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 135; no. 3; pp. 620 - 626.e3
• Main Authors: Flores, Raja M., Pass, Harvey I., Seshan, Venkatraman E., Dycoco, Joseph, Zakowski, Maureen, Carbone, Michele, Bains, Manjit S., Rusch, Valerie W.
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01.03.2008; AATS/WTSA
• Subjects: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiothoracic Surgery; Chi-Square Distribution; Cohort Studies; Female; Follow-Up Studies; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Mesothelioma - mortality; Mesothelioma - pathology; Mesothelioma - surgery; Middle Aged; Neoplasm Staging; Pleura - surgery; Pleural Cavity; Pleural Neoplasms - mortality; Pleural Neoplasms - pathology; Pleural Neoplasms - surgery; Pneumonectomy - methods; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Survival Analysis; Thoracotomy - methods; Treatment Outcome; 14; MPM; EPP; P/D; 10; malignant pleural mesothelioma; pleurectomy/decortication; extrapleural pneumonectomy

The optimal procedure for resection of malignant pleural mesothelioma is controversial, partly because previous analyses include small numbers of patients. We performed a multi-institutional study to increase statistical power to detect significant differences in outcome between extrapleural pneumon...