CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis - Yin, Chengyu; Liu, Boyu; Dong, Zishan; Shi, Sai; Peng, Chenxing; Pan, Yushuang; Bi, Xiaochen; Nie, Huimin; Zhang, Yunwen; Tai, Yan; Hu, Qimiao; Wang, Xuan; et al. (Nature communications, 2024)
Keywords: 13/95; 14/32; 38; 49; 49/91; 631/250/371; 631/378/2607; 631/378/371; 82/51; 82/80; 9/74; 96; 96/31; Animal models; Animals; Ankle; Arthralgia; Arthritis; Arthritis, Gouty; Calcitonin gene-related peptide; Chemokine CXCL5 - genetics; Chemokine CXCL5 - metabolism; Chemotaxis; CXCR2 protein; Dorsal root ganglia; Extravasation; Gout; Humanities and Social Sciences; Humans; Immunomodulation; Inflammation; Joint diseases; Joints (anatomy); Leukocytes (neutrophilic); Male; Mice; multidisciplinary; Neurons; Neutrophils; Nociception; Nociceptors - metabolism; Pain; Pain perception; Rheumatism; Science; Science (multidisciplinary); Sensory neurons; Substance P; Vasodilation