A pan-cancer analysis of the role of USP5 in human cancers

• Published in: Scientific reports Vol. 13; no. 1; pp. 8972 - 19
• Main Authors: Yan, Bokang, Guo, Jiaxing, Deng, Shuang, Chen, Dongliang, Huang, Meiyuan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.06.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208/176; 631/208/68; 631/67/1857; Acetylation; Apoptosis; Cancer; Deoxyribonucleic acid; DNA; DNA damage; DNA methylation; Endothelial cells; Fibroblasts; Genetic markers; Genomes; Genotypes; Humanities and Social Sciences; Metastases; multidisciplinary; Phosphorylation; Prognosis; Science; Science (multidisciplinary); Tumorigenesis; Ubiquitin; Ubiquitin-specific proteinase

Posttranslational modifications (PTM) such as acetylation, deubiquitination, and phosphorylation of proteins, play important roles in various kinds of cancer progression. Ubiquitin-specific proteinase 5 (USP5), a unique member of deubiquitinating enzymes (DUBs) which recognizes unanchored polyubiqui...