Enantioselective synthesis of chiral quinohelicenes through sequential organocatalyzed Povarov reaction and oxidative aromatization

• Published in: Nature communications Vol. 14; no. 1; pp. 3380 - 9
• Main Authors: Li, Chengwen, Shao, Ying-Bo, Gao, Xi, Ren, Zhiyuan, Guo, Chenhao, Li, Meng, Li, Xin
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 08.06.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 119/118; 639/301/923/3931; 639/638/298/398; 639/638/403/935; Acids; Catalysis; Chemical synthesis; Electrochemical analysis; Electrochemistry; Enantiomers; Humanities and Social Sciences; Laboratories; Materials science; multidisciplinary; Phosphoric acid; Photochemicals; Science; Science (multidisciplinary); Substrates

Heterohelicenes are of increasing importance in the fields of materials science, molecular recognition, and asymmetric catalysis. However, enantioselective construction of these molecules, especially by organocatalytic methods, is challenging, and few methods are available. In this study, we synthes...