Emerging mechanisms of lipid peroxidation in regulated cell death and its physiological implications

• Published in: Cell death & disease Vol. 15; no. 11; pp. 859 - 19
• Main Authors: Zheng, Yongxin, Sun, Junlu, Luo, Zhiting, Li, Yimin, Huang, Yongbo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.11.2024; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/80/82; 631/80/86/2365; Animals; Antibodies; Apoptosis; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cell Death; Cytochrome; Enzymes; Fatty acids; Ferroptosis; Free radicals; Humans; Hydrogen; Immunology; Life Sciences; Lipid Peroxidation; Lipids; Metabolism; Molecular modelling; Physiology; Propagation; Regulated Cell Death; Review; Review Article

Regulated cell death (RCD) refers to the form of cell death that can be regulated by various biomacromolecules. Each cell death modalities have their distinct morphological changes and molecular mechanisms. However, intense evidences suggest that lipid peroxidation can be the common feature that ini...